Platelet-Rich Fibrin injected through a cannula to form a fibrin clot used as a stand-alone or combined with fillers represents an alternative leading to high patient satisfaction.
Facial Ageing is a compled process not yet fully understood. Synthetic facial fillers and collagen stimulators, while invaluable tools, do not represent the ideal solution. Many degrade with variability, unwanted illicit responses, and attract water to varying degrees. Thus, autologous blood concentrates have been popularized in aesthetics for several years as a synergistic tool to fill this gap.
Platelet-Rich Plasma (PRP) is by far the most widely utilized due to its ease of extraction, commercial availability, and volume of liquid created in preparation. This latter detail was important in the early stages when clinicians attempted to substitute PRP for facial fillers and equate their efficacy. The volume effect of the autologous concentrate however soon dissipated after injection and while patients enjoyed the improved skin glow and enhancement, the volume effect was short-lived. These supernatants are now being used to improve underlying skin quality, structure, and integrity.
